| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Kleckner, Marissa J (14)
|
PVMACH |
4:56.20 |
4:57.78 |
1.58 |
| 2 |
Blazquez, Lucy A (14)
|
PVPM |
5:09.09 |
5:06.40 |
-2.69 |
| 3 |
Galbraith, Darby E (14)
|
PVMACH |
5:10.94 |
5:09.99 |
-0.95 |
| 4 |
Schuman, Miranda A (13)
|
PVPM |
5:08.09 |
5:11.29 |
3.20 |
| 5 |
Harrington, Abigail M (14)
|
PVPM |
4:55.99 |
5:12.18 |
16.19 |
| 6 |
Kim, Megan J (13)
|
PVPM |
5:23.10 |
5:12.92 |
-10.18 |
| 7 |
Kasemsuwannakaeth, Paige (14)
|
PVMACH |
5:25.49 |
5:14.01 |
-11.48 |
| 8 |
Khorramshahgol, Salma N (13)
|
PVPM |
5:28.11 |
5:25.69 |
-2.42 |
| 9 |
Mcomber, Ella C (14)
|
PVBWST |
5:32.94 |
5:30.88 |
-2.06 |
| 10 |
Foley, Hannah H (13)
|
PVPM |
5:39.09 |
5:32.53 |
-6.56 |
| 11 |
Vannell, Emma G (13)
|
PVBWST |
5:47.00 |
5:35.75 |
-11.25 |
| 12 |
Almeida, Francesca Y (13)
|
PVPM |
5:30.53 |
5:38.80 |
8.27 |
| 13 |
Flickinger, Emma E (13)
|
PVMACH |
5:15.55 |
5:39.50 |
23.95 |
| 14 |
McCullough, Ainsley E (13)
|
PVMACH |
5:31.46 |
5:40.59 |
9.13 |
| 15 |
St Jean, Abigail F (14)
|
PVPM |
|
5:45.02 |
- |
| 16 |
McCullough, Teagan M (13)
|
PVMACH |
6:04.23 |
5:53.28 |
-10.95 |
| 17 |
Soto, Barbara N (13)
|
PVMACH |
|
6:44.96 |
- |