| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Ekanayake, Samantha K (14)
|
MDEST |
5:40.23 |
5:36.51 |
-3.72 |
| 2 |
Li, Mia (13)
|
MDEST |
5:36.38 |
5:41.14 |
4.76 |
| 3 |
Grimes, Logan A (13)
|
MDEST |
6:10.31 |
5:48.65 |
-21.66 |
| 4 |
Gurri, Lucia M (13)
|
MDGBSA |
5:57.77 |
5:50.08 |
-7.69 |
| 5 |
Hendrickson, Margaret R (13)
|
MDEST |
5:55.82 |
5:52.53 |
-3.29 |
| 6 |
Dopson, Mia B (14)
|
MDEST |
6:09.29 |
5:54.26 |
-15.03 |
| 7 |
Gude, Leah M (14)
|
MDEST |
5:47.92 |
5:58.70 |
10.78 |
| 8 |
Arciaga, Savannah J (13)
|
MDGBSA |
5:48.76 |
5:58.88 |
10.12 |
| 9 |
Louis, Katie K (13)
|
MDEST |
6:01.33 |
5:59.09 |
-2.24 |
| 10 |
Hibbert, Breanna M (14)
|
MDEST |
6:00.63 |
6:03.88 |
3.25 |
| 11 |
Nettles, Brionn K (13)
|
MDEST |
6:12.24 |
6:05.20 |
-7.04 |
| 12 |
Mahle, Sophia G (13)
|
MDGBSA |
6:49.52 |
6:06.88 |
-42.64 |
| 13 |
Buchman, Sarah G (13)
|
MDCATY |
6:16.58 |
6:09.13 |
-7.45 |
| 14 |
Trexler, Lauren G (13)
|
MDEST |
6:15.50 |
6:14.60 |
-0.90 |
| 15 |
Short, Rayven L (13)
|
MDEST |
6:32.18 |
6:15.92 |
-16.26 |
| 16 |
Greenwald, Elise R (14)
|
MDEST |
6:10.53 |
6:16.66 |
6.13 |
| 17 |
Liu, Grace Z (13)
|
MDEST |
6:49.01 |
6:20.01 |
-29.00 |
| 18 |
Thornton, Sydney R (14)
|
MDEST |
6:31.07 |
6:20.36 |
-10.71 |
| 19 |
Nielson, Roxana R (13)
|
MDEST |
6:28.45 |
6:29.89 |
1.44 |
| 20 |
Wilson, Taylor M (13)
|
MDEST |
6:20.68 |
6:32.42 |
11.74 |
| 21 |
McArthur, Victoria C (14)
|
MDCAA |
6:12.52 |
6:34.44 |
21.92 |
| 22 |
Mazur, Karolina T (14)
|
MDEST |
6:37.40 |
6:47.23 |
9.83 |
| 23 |
Tray, Zoe J (13)
|
MDGBSA |
6:51.33 |
6:57.71 |
6.38 |
| 24 |
Nelson, Alexandra N (13)
|
MDGBSA |
6:58.07 |
7:03.19 |
5.12 |
| 25 |
Swallow, Penelope N (13)
|
MDGBSA |
6:58.22 |
7:04.06 |
5.84 |
| 26 |
Harvey, Emily E (14)
|
MDGBSA |
7:23.08 |
7:17.39 |
-5.69 |