| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Minott, Asha L (13)
|
MDBAAC |
5:12.04 |
5:22.82 |
10.78 |
| 2 |
Speed, Deanna L (11)
|
MAYY |
5:26.70 |
5:25.26 |
-1.44 |
| 3 |
Laux, Laura V (13)
|
MAYY |
5:39.60 |
5:33.27 |
-6.33 |
| 4 |
Pittala, Sreeya (12)
|
MAUN |
|
5:36.05 |
- |
| 5 |
Froman, Emily J (13)
|
MAYY |
|
5:48.69 |
- |
| 6 |
Williams, Nacala (11)
|
PVDCPR |
6:40.84 |
6:28.06 |
-12.78 |
| 7 |
Miller, Zoe E (16)
|
MDBCSC |
6:40.34 |
6:30.49 |
-9.85 |
| 8 |
Minalu, Rediat (13)
|
PVDCPR |
7:39.23 |
6:51.10 |
-48.13 |
| 9 |
Zhang, Renee y (11)
|
MDRAC |
6:53.95 |
6:51.80 |
-2.15 |
|
Cason, Amatullah B (11)
|
MDBCSC |
|
NS |
- |
|
Coates Woods, Decensae J (11)
|
MDBCSC |
|
NS |
- |
|
Holiday, Jordin D (12)
|
MDBCSC |
|
NS |
- |
|
Regert, Alexandra C (12)
|
MDJCC |
8:18.28 |
NS |
- |