| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Groff, Avery (15)
|
MAYY |
4:51.40 |
4:53.26 |
1.86 |
| 2 |
Strayer, Catherine (15)
|
MAYY |
4:59.07 |
5:03.36 |
4.29 |
| 3 |
Merrifield, Morgan L (17)
|
MAYY |
5:09.40 |
5:08.64 |
-0.76 |
| 4 |
Butera, Arabella G (14)
|
MAYY |
5:02.58 |
5:10.43 |
7.85 |
| 5 |
Melick, Abigail G (14)
|
MDBAAC |
5:12.53 |
5:17.83 |
5.30 |
| 6 |
Way, Emily J (12)
|
MAYY |
|
5:19.02 |
- |
| 7 |
Fabian, Carol M (13)
|
MAYY |
5:20.30 |
5:27.17 |
6.87 |
| 8 |
Davies, Emily M (16)
|
MDHSST |
5:28.24 |
5:31.54 |
3.30 |
| 9 |
John, Grace L (14)
|
MDBAAC |
5:42.60 |
5:31.70 |
-10.90 |
| 10 |
Weichseldorfer, Sarah M (12)
|
MAYY |
5:35.40 |
5:41.13 |
5.73 |
| 11 |
Nelson, Sarah L (15)
|
MDBAAC |
5:42.61 |
5:41.55 |
-1.06 |
| 12 |
Kim, Allison G (13)
|
MDEST |
6:01.09 |
5:58.46 |
-2.63 |
| 13 |
Huber, Kalise M (11)
|
MDBAAC |
6:16.65 |
5:59.50 |
-17.15 |
| 14 |
Ledoux, Teysha L (17)
|
NEPRDE |
6:26.78 |
6:02.16 |
-24.62 |
| 15 |
Dolan, Haylee P (12)
|
NEPRDE |
6:38.74 |
6:02.40 |
-36.34 |
| 16 |
Wells, Madison K (13)
|
MDBCSC |
|
6:10.35 |
- |
| 17 |
Pflieger, Zoe E (18)
|
MDBCSC |
6:01.57 |
6:11.81 |
10.24 |
| 18 |
Holiday, Jordin D (14)
|
MDBCSC |
6:30.90 |
6:25.42 |
-5.48 |
| 19 |
MacFarlane, Andrea (17)
|
NEPRDE |
5:25.33 |
6:41.12 |
75.79 |
| 20 |
Mbatia, Akayah G (11)
|
NEPRDE |
7:42.90 |
6:54.29 |
-48.61 |
| 21 |
Muhammad, Ndera S (16)
|
MDBCSC |
|
7:37.14 |
- |
| 22 |
Cabbagestalk, Amanie J (13)
|
MDUN |
|
7:37.65 |
- |