| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Riordan, Amy L (14)
|
GAASL |
4:54.64 |
4:39.36 |
-15.28 |
| 2 |
Perez, Giulliana (14)
|
FLSTAR |
4:41.10 |
4:41.39 |
0.29 |
| 3 |
McCurdy, Caroline G (13)
|
NEBGSC |
4:51.56 |
4:43.31 |
-8.25 |
| 4 |
Wirtanen, Ava R (14)
|
NEBGSC |
4:57.77 |
4:51.32 |
-6.45 |
| 5 |
Munger, Audrey A (14)
|
GAASL |
5:03.51 |
4:52.21 |
-11.30 |
| 6 |
Muzii, Beverly R (14)
|
FGMCDA |
5:08.57 |
5:05.71 |
-2.86 |
| 7 |
Hernandez, Isabella (13)
|
ZZLACE |
5:14.14 |
5:06.52 |
-7.62 |
| 7 |
Nagy, Julia K (13)
|
FLSTAR |
5:24.85 |
5:06.52 |
-18.33 |
| 9 |
Robson, Stella c (14)
|
NEWTST |
5:21.69 |
5:12.03 |
-9.66 |
| 10 |
Groves, Sophie M (13)
|
GAASL |
|
5:24.65 |
- |
| 11 |
Dilone, Yenari Y (13)
|
ZZTITA |
5:34.73 |
5:34.07 |
-0.66 |
| 12 |
Olivares, Liana (13)
|
ZZLACE |
5:53.51 |
5:50.95 |
-2.56 |
| 13 |
Infante Carrera, Andrea A. (14)
|
ZZTITA |
6:00.01 |
5:59.64 |
-0.37 |
| 14 |
Oren, Maya (13)
|
FGPST |
6:16.23 |
6:10.93 |
-5.30 |
|
Callahan, Anne-mari S (13)
|
NEBGSC |
5:12.93 |
NS |
- |
|
Medina Ramos, Paola M (13)
|
ZZMAH |
5:41.40 |
NS |
- |