| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Hynes, Kylee N (15)
|
MAGPAC |
4:48.13 |
4:52.67 |
4.54 |
| 2 |
Becker, Samantha (15)
|
MALMOR |
5:05.41 |
4:55.01 |
-10.40 |
| 3 |
Disanti, Brianna K (16)
|
MAJW |
5:04.27 |
4:55.28 |
-8.99 |
| 4 |
Jones, Megan E (18)
|
MAWAC |
4:52.48 |
5:01.80 |
9.32 |
| 5 |
Iannacone, Megan C (15)
|
MAGSA |
5:24.67 |
5:01.82 |
-22.85 |
| 6 |
Fleisher, Sarah R (17)
|
MAJW |
4:59.58 |
5:03.21 |
3.63 |
| 7 |
Link, Natalie C (15)
|
MAPSC |
5:14.41 |
5:05.37 |
-9.04 |
| 8 |
Pryshchenko, Katya A (15)
|
MAMSA |
5:05.46 |
5:06.36 |
0.90 |
| 9 |
Robbins, Lindsay E (15)
|
MAECCC |
5:04.59 |
5:09.64 |
5.05 |
| 10 |
May, Georgia S (15)
|
MADYD |
5:38.76 |
5:10.41 |
-28.35 |
| 11 |
Blazure, Mckayla (16)
|
MABLUE |
5:07.10 |
5:11.60 |
4.50 |
| 12 |
Nelson, Caroline A (16)
|
MAEMAC |
5:38.25 |
5:22.35 |
-15.90 |
| 13 |
Schuster, Danielle N (16)
|
MASEA |
5:49.12 |
5:24.19 |
-24.93 |
| 14 |
May, Alexandra E (17)
|
MADYD |
5:39.19 |
5:24.58 |
-14.61 |
| 15 |
Raphaely, Kathryn D (18)
|
MAFCA |
5:17.53 |
5:36.32 |
18.79 |