| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Freihofer, Anna E (15)
|
OHRCDB |
2:26.61 |
2:23.09 |
-3.52 |
| 2 |
Redden, Sarah G (15)
|
OHPCY |
2:29.78 |
2:27.36 |
-2.42 |
| 3 |
Crowell, Mykaela L (16)
|
INWCFY |
2:33.97 |
2:32.40 |
-1.57 |
| 4 |
Thomas, Faith (17)
|
INYMMI |
2:34.86 |
2:37.87 |
3.01 |
| 5 |
Hatcher, Sophia (15)
|
INWCFY |
2:33.66 |
2:38.80 |
5.14 |
| 6 |
Young, Shauna (16)
|
INWCFY |
2:39.14 |
2:39.48 |
0.34 |
| 7 |
Telfer, Claire (17)
|
KYBYB |
2:58.81 |
2:41.21 |
-17.60 |
| 8 |
Cyrus, Kelsey M (17)
|
KYAAY |
2:43.98 |
2:46.22 |
2.24 |
| 9 |
Ellis, Taylor J (16)
|
KYBYB |
2:45.49 |
2:48.10 |
2.61 |
| 10 |
Mihaljevic, Meghan M (17)
|
OHRCDB |
2:45.85 |
2:48.81 |
2.96 |
| 11 |
Greiwe, Amanda P (16)
|
KYBYB |
2:44.09 |
2:49.88 |
5.79 |
| 12 |
Biedenbach, Kieren M (15)
|
OHPCY |
|
2:55.12 |
- |
| 13 |
Schaekel, Ayn-Margaret (15)
|
INWCFY |
3:06.59 |
3:03.03 |
-3.56 |
| 14 |
Cagle, Kathleen E (16)
|
OHPCY |
|
3:11.71 |
- |
|
Hays, Emily G (17)
|
KYAAY |
3:27.18 |
DQ |
- |
|
Meeks, Katelyn (15)
|
OHPCYP |
2:49.30 |
NS |
- |
|
Fox, Isabel F (15)
|
INYMMI |
2:31.82 |
NS |
- |
|
Miller, Gretchen A (15)
|
OHBASH |
2:37.42 |
NS |
- |
|
Thornburg, Mary A (16)
|
KYAAY |
2:33.32 |
NS |
- |
|
Hupp, Hannah M (16)
|
KYAAY |
2:40.21 |
NS |
- |