| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Lee, Elena G (12)
|
MDEST |
6:01.00 |
5:47.57 |
-13.43 |
| 2 |
O'Brien, Makenzie M (12)
|
MDEST |
6:03.74 |
5:51.96 |
-11.78 |
| 3 |
Petriccione, Melania C (12)
|
MRRA |
5:59.17 |
5:53.70 |
-5.47 |
| 4 |
Heron, Nina B (11)
|
MDRAC |
6:14.21 |
5:58.67 |
-15.54 |
| 5 |
Anderson, Samantha R (11)
|
MRLIAC |
6:02.88 |
6:02.32 |
-0.56 |
| 6 |
Carvente, Ashley (11)
|
CTZEUS |
6:09.31 |
6:02.47 |
-6.84 |
| 7 |
So, Leni A (11)
|
MRLIAC |
6:03.58 |
6:03.00 |
-0.58 |
| 8 |
Handwerger, Jenna E (11)
|
MDEST |
6:09.27 |
6:04.89 |
-4.38 |
| 9 |
Rothrock, Abigale P (12)
|
MDCAA |
6:25.77 |
6:12.49 |
-13.28 |
| 10 |
McDonald, Cara B (11)
|
MRLIAC |
6:17.78 |
6:16.26 |
-1.52 |
| 11 |
Feliz, Lucy C (11)
|
MDSPRC |
6:36.39 |
6:17.44 |
-18.95 |
| 12 |
Pohlhaus, Ayla B (11)
|
MDEST |
6:31.33 |
6:18.11 |
-13.22 |
| 13 |
Rinker, Adrienne G (12)
|
MDEST |
6:32.36 |
6:19.32 |
-13.04 |
| 14 |
Cowley, Jenna S (12)
|
MDEST |
6:40.24 |
6:20.62 |
-19.62 |
| 15 |
Henley, Emily M (11)
|
MDFSC |
6:42.80 |
6:23.51 |
-19.29 |
| 16 |
Dong, Emily C (11)
|
MDCAA |
6:37.80 |
6:28.59 |
-9.21 |
| 17 |
McCullough, Saryn R (12)
|
MAWEST |
6:46.88 |
6:30.49 |
-16.39 |