| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Byrne, Kelly P (16)
|
MRWEST |
4:45.67 |
4:34.48 |
-11.19 |
| 2 |
Walsh, Jessica M (15)
|
MRLIE |
4:50.03 |
4:47.88 |
-2.15 |
| 3 |
Vos, Brooke C (15)
|
MREAST |
4:45.90 |
4:48.31 |
2.41 |
| 4 |
Kang, Joy (14)
|
MRWEST |
4:45.22 |
4:50.05 |
4.83 |
| 5 |
Martinez-Reyes, Tristinye J (15)
|
MRLIE |
4:54.15 |
4:54.20 |
0.05 |
| 6 |
Konop, Rebecca G (16)
|
MRLIE |
4:48.85 |
4:56.36 |
7.51 |
| 7 |
Haimson, Emma A (15)
|
MRUN |
4:59.59 |
4:59.54 |
-0.05 |
| 8 |
Martinez-Reyes, Areiannah J (17)
|
MRLIE |
5:07.84 |
4:59.86 |
-7.98 |
| 9 |
Kang, Sunny (12)
|
MRWEST |
5:14.34 |
5:00.97 |
-13.37 |
| 10 |
O'Connell, Siobhan B (17)
|
MRLIE |
5:02.81 |
5:12.20 |
9.39 |
| 11 |
Guglielmo, Ava S (15)
|
MRLIE |
5:04.80 |
5:15.04 |
10.24 |
| 12 |
Favata, Ashlee C (16)
|
MRLIE |
5:22.68 |
5:17.76 |
-4.92 |
| 13 |
Favata, Alicia M (16)
|
MRLIE |
5:39.60 |
5:20.95 |
-18.65 |
| 14 |
Ramirez, Lily L (12)
|
MRYFD |
|
5:21.76 |
- |
| 15 |
Chan, Megan N (15)
|
MRLIE |
5:30.39 |
5:24.11 |
-6.28 |
|
Immel, Elizabeth A (17)
|
MRLIE |
5:08.60 |
NS |
- |
|
McKenna, Mary K (16)
|
MRLIE |
4:19.81 |
NS |
- |
|
Singh, Cristina P (17)
|
MRLIE |
4:55.19 |
NS |
- |
|
Torello-Viera, Martina S (17)
|
MREAST |
4:44.26 |
NS |
- |
|
Stoll, Olivia P (17)
|
MREAST |
5:11.05 |
NS |
- |