| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Wiese, Zoey G (13)
|
MREAST |
2:45.10 |
2:42.91 |
-2.19 |
| 2 |
Vitti, Georgia H (12)
|
MREAST |
2:44.44 |
2:46.57 |
2.13 |
| 3 |
Cabello, Mackenzie E (12)
|
MREAST |
2:45.79 |
2:49.16 |
3.37 |
| 4 |
Iacobazzi, Alba (12)
|
MREAST |
2:55.28 |
2:52.66 |
-2.62 |
| 5 |
Nalepka, Katherine J (14)
|
MREAST |
|
2:55.36 |
- |
| 6 |
Hogue, Beatrice A (11)
|
MREAST |
2:54.48 |
3:04.15 |
9.67 |
| 7 |
An, Gabrielle E (14)
|
MREAST |
3:00.50 |
3:08.33 |
7.83 |
| 8 |
Wang, Melissa R (13)
|
MREAST |
2:56.44 |
3:08.97 |
12.53 |
| 9 |
Blaho, Fiona A (10)
|
MREAST |
3:01.88 |
3:10.68 |
8.80 |
| 10 |
Atkins, Sophia A (12)
|
MREAST |
3:22.56 |
3:20.54 |
-2.02 |
|
Frey, Dolores S (12)
|
MREAST |
2:50.88 |
NS |
- |