| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Scott, Leah S (15)
|
MDYCM |
2:26.16 |
2:24.60 |
-1.56 |
| 2 |
Entner, Rebecca F (16)
|
MDBAAC |
2:25.47 |
2:28.28 |
2.81 |
| 3 |
Woods, Mary D (15)
|
MDGBSA |
2:32.04 |
2:28.92 |
-3.12 |
| 4 |
O'Shaughnessy, Amanda J (17)
|
MDGBSA |
2:23.17 |
2:30.60 |
7.43 |
| 5 |
Fisher, Casey L (11)
|
MDRAC |
2:34.55 |
2:33.93 |
-0.62 |
| 6 |
Bosenberg, Camila (16)
|
MDGBSA |
2:26.98 |
2:34.57 |
7.59 |
| 7 |
Hogue, Sofie M (11)
|
MDRAC |
2:35.33 |
2:35.75 |
0.42 |
| 8 |
Zaidi, Amina F (15)
|
MDYCM |
|
2:37.93 |
- |
| 9 |
Wenstrand, Caroline G (16)
|
MDYCM |
2:36.23 |
2:39.19 |
2.96 |
| 10 |
Kalinowski, Victoria O (12)
|
MDBAAC |
2:39.43 |
2:40.09 |
0.66 |
| 11 |
Hanna, Bella M (11)
|
MDBAAC |
2:39.70 |
2:42.14 |
2.44 |
| 12 |
Ellsworth, Ashley P (10)
|
MDBAAC |
|
2:43.58 |
- |
| 13 |
Tiberio, Layla M (15)
|
MDYCM |
2:45.11 |
2:45.72 |
0.61 |
| 14 |
Yienger, Jessica A (17)
|
MDYCM |
|
2:48.92 |
- |
| 15 |
Blair, Kaylee M (12)
|
MDBAAC |
|
2:50.59 |
- |
| 16 |
Pflieger, Zoe E (17)
|
MDBCSC |
2:46.86 |
3:00.93 |
14.07 |
|
Schwab, Hannah C (12)
|
MDGBSA |
2:34.90 |
NS |
- |
|
Tse, Courtney C (16)
|
MDYCM |
2:34.97 |
NS |
- |