| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Zaidi, Alexia Y (12)
|
MDCAC |
5:59.10 |
5:51.04 |
-8.06 |
| 2 |
Gurri, Lucia M (12)
|
MDGBSA |
5:59.58 |
5:57.77 |
-1.81 |
| 3 |
Hendrickson, Margaret R (12)
|
MDEST |
5:55.82 |
5:58.62 |
2.80 |
| 4 |
Hogue, Sofie M (11)
|
MDRAC |
5:58.64 |
5:58.68 |
0.04 |
| 5 |
Schmeckpeper, Emily D (12)
|
MDRAC |
5:59.55 |
5:59.12 |
-0.43 |
| 6 |
Young, Emerson G (12)
|
MDACA |
6:22.53 |
6:02.91 |
-19.62 |
| 7 |
Bostian, Rachael E (12)
|
MDFCY |
6:16.60 |
6:06.95 |
-9.65 |
| 8 |
Witt, Sophia J (12)
|
MDFSC |
6:18.47 |
6:09.90 |
-8.57 |
| 9 |
Graham, Rilee E (11)
|
MDACA |
6:35.74 |
6:20.13 |
-15.61 |
| 10 |
Schmidt, Gabrielle R (12)
|
MDCAC |
6:18.38 |
6:20.16 |
1.78 |
| 11 |
Mancinelli, Laura A (12)
|
MDFAST |
6:58.72 |
6:31.11 |
-27.61 |
| 12 |
Schwab, Hannah C (12)
|
MDGBSA |
7:15.11 |
6:31.80 |
-43.31 |
| 13 |
Tolle, Brooke (12)
|
MDFSC |
6:41.16 |
6:32.05 |
-9.11 |
| 14 |
Carter, Grace O (11)
|
MDFAST |
6:52.99 |
6:33.25 |
-19.74 |
| 15 |
Rice, Stephanie M (12)
|
MDMAS |
6:38.65 |
6:43.11 |
4.46 |
| 16 |
Cason, Amatullah B (11)
|
MDBCSC |
7:03.88 |
7:07.31 |
3.43 |
|
Taylor, Marin K (12)
|
MDMAS |
6:52.50 |
DQ |
- |
|
Keller, Erin B (12)
|
MDGBSA |
7:42.31 |
NS |
- |