| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Farkas, Naomi U (17)
|
MDCAA |
2:34.08 |
2:38.97 |
4.89 |
| 2 |
Nettles, Brionn K (15)
|
MDEST |
2:39.14 |
2:39.15 |
0.01 |
| 3 |
Gurri, Gabriella M (15)
|
MDGBSA |
2:40.44 |
2:40.67 |
0.23 |
| 4 |
Hendrickson, Margaret R (15)
|
MDEST |
2:41.20 |
2:43.38 |
2.18 |
| 5 |
Harris, Madison L (17)
|
MDGBSA |
2:48.09 |
2:44.20 |
-3.89 |
| 6 |
Schwab, Hannah C (15)
|
MDGBSA |
2:43.54 |
2:44.24 |
0.70 |
| 7 |
Gurri, Lucia M (15)
|
MDGBSA |
2:40.68 |
2:46.14 |
5.46 |
| 8 |
Sheridan, Olivia C (15)
|
MDEST |
2:40.57 |
2:46.85 |
6.28 |
| 9 |
Liu, Grace Z (15)
|
MDEST |
2:41.08 |
2:47.37 |
6.29 |
| 10 |
Woods, Mary D (18)
|
MDGBSA |
2:46.86 |
2:49.12 |
2.26 |
| 11 |
DeMario, Emma R (15)
|
MDCCY |
2:53.75 |
2:52.88 |
-0.87 |
| 12 |
Briggs, Emily R (16)
|
MDEST |
2:58.24 |
2:53.07 |
-5.17 |
| 13 |
Vandewinckel, Olivia A (12)
|
MDGBSA |
3:00.52 |
2:54.26 |
-6.26 |
| 14 |
Craig, Mia R (14)
|
MDCCY |
2:52.22 |
3:00.81 |
8.59 |
| 15 |
Quinn, Olivia G (11)
|
MDGMAC |
2:57.78 |
3:01.91 |
4.13 |
| 16 |
Mazur, Karolina T (16)
|
MDEST |
3:03.87 |
3:04.48 |
0.61 |
| 17 |
Klopouh, Milana S (16)
|
MDEST |
2:59.39 |
3:07.31 |
7.92 |
| 18 |
Gurri, Maddalena G (11)
|
MDGBSA |
3:47.44 |
3:20.18 |
-27.26 |
|
Swallow, Penelope N (15)
|
MDGBSA |
2:54.67 |
NS |
- |
|
Beck, Meredith L (16)
|
MDHOCO |
2:49.53 |
NS |
- |
|
Burger, Carmella L (16)
|
MDEST |
3:04.36 |
NS |
- |
|
Pue, Abigail E (18)
|
MDCCY |
2:58.00 |
NS |
- |