| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Griffin, Lillian E (12)
|
MDEST |
5:46.51 |
5:23.90 |
-22.61 |
| 2 |
Barnes, Holland A (12)
|
MDEST |
5:38.99 |
5:24.76 |
-14.23 |
| 3 |
Takasaki, Catherine Ann K (12)
|
MDEST |
|
5:36.74 |
- |
| 4 |
Zavala, Alina V (12)
|
MDEST |
|
5:40.42 |
- |
| 5 |
Hawkins, Jillian E (11)
|
MDEST |
5:39.26 |
5:41.57 |
2.31 |
| 6 |
Lee, Elena G (11)
|
MDEST |
5:42.78 |
5:45.09 |
2.31 |
| 7 |
Carver, Olivia C (11)
|
MDEST |
5:51.95 |
5:50.98 |
-0.97 |
| 8 |
O'Brien, Makenzie M (11)
|
MDEST |
5:53.07 |
5:54.49 |
1.42 |
| 9 |
Kinnear, Emily L (12)
|
MDEST |
|
6:01.20 |
- |
| 10 |
Gassman, Madeline G (11)
|
MDEST |
6:05.24 |
6:01.73 |
-3.51 |
| 11 |
Mahoney, Sarah C (12)
|
MDMAS |
|
6:01.99 |
- |
| 12 |
Lin, Constance Y (11)
|
MDEST |
6:05.42 |
6:04.40 |
-1.02 |
| 13 |
Kim, Allison G (12)
|
MDEST |
6:01.65 |
6:05.17 |
3.52 |
| 14 |
Mackey, Andrea (Andi) J (12)
|
MDEST |
|
6:10.09 |
- |
| 15 |
Sane, Shriya A (12)
|
MDEST |
6:28.33 |
6:20.75 |
-7.58 |
| 16 |
Seligman, Elyse G (11)
|
MDEST |
6:38.42 |
6:22.08 |
-16.34 |
|
Gude, Lila M (12)
|
MDEST |
5:57.08 |
DQ |
- |