| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Stokes, Kennedy A (13)
|
MDBCSC |
5:27.31 |
5:16.64 |
-10.67 |
| 2 |
Mackey, Andrea J (14)
|
MDEST |
5:25.85 |
5:21.64 |
-4.21 |
| 3 |
Lin, Constance Y (13)
|
MDEST |
5:20.63 |
5:22.44 |
1.81 |
| 4 |
Cowley, Jenna S (13)
|
MDEST |
5:32.39 |
5:29.50 |
-2.89 |
| 5 |
Birdsall, Caroline R (13)
|
MDEST |
|
5:40.98 |
- |
| 6 |
Rupard, Alexis D (13)
|
MDSMDA |
|
5:41.22 |
- |
| 7 |
Liu, Aceline Y (14)
|
MDBAAC |
6:28.85 |
5:45.12 |
-43.73 |
| 8 |
Wollenweber, Olivia B (13)
|
MDEST |
|
5:51.29 |
- |
| 9 |
Bonney, MacKenna L (13)
|
MDFAST |
6:36.45 |
6:00.20 |
-36.25 |
| 10 |
Orsburn, Tatiana M (14)
|
MDUN |
|
6:30.24 |
- |
|
Hudson, Chase M (14)
|
MDEST |
5:58.77 |
DQ |
- |
|
Arsenault, Tara H (14)
|
MDNBAC |
5:23.33 |
DQ |
- |