| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Horn, Kim S (15)
|
MDSPY |
2:28.68 |
2:26.19 |
-2.49 |
| 2 |
Lee, Allyson V (16)
|
MDSPY |
2:27.65 |
2:26.76 |
-0.89 |
| 3 |
Starrett, Julia M (15)
|
MDNAAC |
2:31.50 |
2:31.63 |
0.13 |
| 4 |
Bruns, Rachel E (17)
|
MDMSC |
2:29.79 |
2:32.36 |
2.57 |
| 5 |
Jocic, Mia (15)
|
MDNAAC |
2:34.27 |
2:32.69 |
-1.58 |
| 6 |
Bladzinski, Kayla A (15)
|
MDNAAC |
2:34.72 |
2:33.29 |
-1.43 |
| 7 |
Patty, Eliza K (15)
|
MDSPRC |
2:41.30 |
2:34.31 |
-6.99 |
| 8 |
Woods, Mary D (16)
|
MDGBSA |
2:39.02 |
2:38.88 |
-0.14 |
| 9 |
Jin, Victoria S (16)
|
MDMSC |
2:37.63 |
2:40.43 |
2.80 |
| 10 |
Lavin, Sydney C (15)
|
MDMSC |
2:37.35 |
2:42.72 |
5.37 |
| 11 |
Donegan, Angela D (15)
|
MDSPRC |
2:47.81 |
2:43.32 |
-4.49 |
| 12 |
Knauer, Grace E (15)
|
MDSPRC |
2:41.89 |
2:46.29 |
4.40 |
|
Nolan, Ann Marie C (18)
|
MDNAAC |
2:40.33 |
NS |
- |
|
Valkenberg, Sophia H (17)
|
MDMSC |
2:29.26 |
NS |
- |
|
Trella, Isabelle K (15)
|
MDNAAC |
2:35.50 |
NS |
- |
|
Aguirre-Nicholson, Elysia E (16)
|
MDSPRC |
2:57.40 |
NS |
- |
|
Litynski, McKenna L (15)
|
MDCBAC |
2:28.26 |
NS |
- |
|
Howard, Samantha G (15)
|
MDYCM |
3:03.36 |
NS |
- |