| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Lane, Alexandra M (12)
|
OKTAC |
5:02.19 |
5:08.31 |
6.12 |
| 2 |
Elliott, Kiersten M (12)
|
MVANDR |
5:36.38 |
5:16.83 |
-19.55 |
| 3 |
Cook, Taylor J (12)
|
OKUNAT |
5:28.61 |
5:17.20 |
-11.41 |
| 4 |
Roper, Claire M (12)
|
LARRAC |
5:26.39 |
5:19.15 |
-7.24 |
| 5 |
Mace, Madeleine C (12)
|
MVANDR |
5:31.49 |
5:26.29 |
-5.20 |
| 6 |
Morykwas, Rowan J (12)
|
OKJTSC |
5:54.61 |
5:30.82 |
-23.79 |
| 7 |
Rick, Rylee J (12)
|
GUCATS |
6:12.75 |
5:43.37 |
-29.38 |
| 8 |
Grotelueschen, Grace M (12)
|
OKAESC |
6:10.55 |
6:05.93 |
-4.62 |
| 9 |
Degreve, Ella A (12)
|
OKAESC |
7:09.32 |
6:17.29 |
-52.03 |
| 10 |
Blake, Sophia R (12)
|
OKBAC |
|
6:32.17 |
- |
| 11 |
Butler, Faith A (12)
|
MVANDR |
|
6:49.03 |
- |
| 12 |
Widowski, Emily R (12)
|
OKBSC |
|
6:55.34 |
- |
|
Faulkner, Alysandra B (12)
|
GUCATS |
5:07.69 |
DNF |
-307.69 |