| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Yang, Georgia M (13)
|
PVASA |
4:46.07 |
4:41.10 |
-4.97 |
| 2 |
Brooks, Ava M (14)
|
PVASA |
4:51.56 |
4:51.74 |
0.18 |
| 3 |
Novak, Victoria N (14)
|
MDBAAC |
5:01.29 |
4:53.27 |
-8.02 |
| 4 |
Ivanovskaya, Veronica (14)
|
PVRMSC |
5:03.28 |
5:01.09 |
-2.19 |
| 5 |
Cosgrove, Alexandria R (14)
|
PVASA |
4:57.47 |
5:02.18 |
4.71 |
| 6 |
Salazar, Rachel (13)
|
PVMSSC |
5:15.64 |
5:04.29 |
-11.35 |
| 7 |
Gotham, Madison (14)
|
MDHFY |
6:20.85 |
5:08.92 |
-71.93 |
| 8 |
Melick, Abigail G (14)
|
MDBAAC |
5:17.80 |
5:16.97 |
-0.83 |
| 9 |
Yu, Michelle W (14)
|
PVMSSC |
5:14.16 |
5:17.91 |
3.75 |
| 10 |
Clark, Micah S (14)
|
PVDCPR |
5:33.28 |
5:24.45 |
-8.83 |