| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
McConagha, Mackenzie B (16)
|
PVNCAP |
5:03.12 |
5:12.50 |
9.38 |
| 2 |
Tsai, Kaitlyn E (15)
|
PVNCAP |
5:21.57 |
5:17.75 |
-3.82 |
| 3 |
Long, Lauren E (15)
|
PVBWST |
5:42.17 |
5:24.43 |
-17.74 |
| 4 |
Stefanyshyn, Andrea M (16)
|
PVNCAP |
5:26.30 |
5:36.76 |
10.46 |
| 5 |
Melnikova, Anastasia Y (17)
|
PVSDS |
5:35.64 |
5:51.28 |
15.64 |
| 6 |
Hopkins, Delaney B (15)
|
MDBAAC |
6:06.27 |
5:53.17 |
-13.10 |
| 7 |
Tonnu, Valerie H (15)
|
PVRIPS |
6:21.36 |
6:04.45 |
-16.91 |
| 8 |
Burns, Alexis M (15)
|
PVFXFX |
6:11.83 |
6:17.80 |
5.97 |
| 9 |
Heninger, Anna M (15)
|
PVFXFX |
6:36.32 |
6:25.06 |
-11.26 |
| 10 |
Amsler, Kendall F (15)
|
MDBAAC |
6:19.01 |
6:26.61 |
7.60 |
|
Smith, Sade S (16)
|
PVOCCS |
6:44.48 |
NS |
- |