| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Maurer, Elise M (14)
|
ILHEAT |
5:23.56 |
5:41.91 |
18.35 |
| 2 |
Best, Emma K (13)
|
ILACAD |
5:45.11 |
5:45.96 |
0.85 |
| 3 |
Kulasinsky, Adrienne J (13)
|
ILUN-F |
6:02.58 |
6:04.19 |
1.61 |
| 4 |
Terry, Olivia R (13)
|
ILHEAT |
5:50.33 |
6:07.04 |
16.71 |
| 5 |
Fuller, Payton J (14)
|
ILHEAT |
6:23.76 |
6:07.22 |
-16.54 |
| 6 |
Millhollin, Brooklyn M (13)
|
ILDDST |
6:11.16 |
6:07.81 |
-3.35 |
| 7 |
Gulley, Georgette G (13)
|
ILACAD |
6:06.69 |
6:17.61 |
10.92 |
| 8 |
Bellis, Wrigley M (13)
|
ILBNSC |
6:26.79 |
6:28.22 |
1.43 |
| 9 |
Freeburg, Brianna E (14)
|
ILHEAT |
6:32.48 |
6:28.38 |
-4.10 |
|
Johnson, Ava G (14)
|
ILFFSC |
6:10.95 |
NS |
- |