| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Coe, Angela A (15)
|
ILHEAT |
4:49.67 |
5:02.93 |
13.26 |
| 2 |
Pearson, Allison E (17)
|
ILBNSC |
5:11.74 |
5:16.64 |
4.90 |
| 3 |
Withers, Katherine D (17)
|
ILPAWW |
5:44.47 |
5:32.31 |
-12.16 |
| 4 |
Haerr, Olivia J (15)
|
ILBNSC |
5:32.96 |
5:39.10 |
6.14 |
| 5 |
Kulasinsky, Katrina E (15)
|
ILUN-F |
5:31.34 |
5:45.98 |
14.64 |
| 6 |
Jenkins, Erin R (15)
|
ILFFSC |
5:47.29 |
5:49.37 |
2.08 |
| 7 |
McMurry, Olivia L (15)
|
ILHEAT |
6:28.42 |
5:53.79 |
-34.63 |
| 8 |
Cook, Samantha A (15)
|
ILHEAT |
5:24.96 |
5:56.95 |
31.99 |
| 9 |
Oelze, Eden G (15)
|
ILHEAT |
6:11.84 |
6:02.29 |
-9.55 |
| 10 |
Ray, Kaelyn H (16)
|
ILPAWW |
5:51.29 |
6:02.79 |
11.50 |
| 11 |
Mesplay, Katie J (15)
|
ILHEAT |
6:07.88 |
6:16.95 |
9.07 |
| 12 |
Nelson, Emma A (15)
|
ILFFSC |
|
6:38.82 |
- |
| 13 |
Marcordes, Linda A (15)
|
ILFFSC |
|
6:49.54 |
- |
| 14 |
Rogers, Ella E (16)
|
ILUPDT |
|
6:59.45 |
- |